The Second Best Hospital in the Galaxy premieres February 23, 2024 on Prime Video. The series was created by Cirocco Dunlap (Baymax!) with animation by Titmouse Studios.

Guest stars for season one include Tracee Ellis Ross (Black-ish), Bowen Yang (Saturday Night Live), Abbi Jacobson (Broad City), Jay Ellis (Top Gun: Maverick), Andrew Dismukes (Saturday Night Live), Lennon Parham (Minx), Gary Anthony Williams (Night Court) and filmmaker John Waters.

Series regulars include Maya Rudolph, Natasha Lyonne, Keke Palmer, Stephanie Hsu, Kieran Culkin and Sam Smith.

Synopsis: The Second Best Hospital in the Galaxy follows renowned surgeons Dr. Sleech and Dr. Klak as they tackle anxiety-eating parasites, illegal time loops, and deep-space STIS. In season one, doctors Sleech and Klak take on a highly dangerous and potentially groundbreaking case and, in doing so, put existence itself in jeopardy. Although considering their dismal personal lives, oblivion might be an improvement.